10. Kirksville, Missouri
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Kirksville, Missouri, dropped from its fourth-place spot in 2015 to No. 10 this year, with a median home price increase of $8,600. It's home to both Truman State University, established in 1867, and A.T. Still University, established in 1892. Truman State University is the top public university in the Midwest, according to the 2017 Best Colleges ranking from U.S. News and World Report. Kirksville is located just over 200 miles northwest of St. Louis.
